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MARBL
MARBL is a free (GPL) system to index the text portions of GenBank and associated NLM abstracts. Based on Mumps and the MDH.
http://www.cs.uni.edu/~okane/source/MARBL/proc1.html
Uni.edu ~
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Geneious
This research software is designed for biologists and not computer scientists. It combines all the major DNA and protein sequence analysis tools into one software solution.
http://www.geneious.com
Geneious.com ~
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biOpen
Commercial Mac OS X sequence analysis and structure visualization software.
http://www.lightwave-scientific.com/Resources/biOpen.pdf
Lightwave-scientific.com ~
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